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定量测定的免疫反应和睡眠模式<em>果蝇</em
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Immunology and Infection
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JoVE Journal Immunology and Infection
Quantitative Measurement of the Immune Response and Sleep in Drosophila
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定量测定的免疫反应和睡眠模式<em>果蝇</em

DOI:
10.3791/4355-v

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12:16 min

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December 04, 2012

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, ,
1Center for Sleep and Circadian Neurobiology,University of Pennsylvania Perelman School of Medicine

Chapters

  • 00:05Title
  • 01:33Bacterial Injection of Drosophila
  • 04:40Determining the Bacterial Load
  • 06:26Measuring NFkB Activity in Infected Flies
  • 09:51Representative Measurements of Sleep and Immune Function During a Bacterial Infection
  • 11:50Conclusion

Summary

Automatic Translation

Automatic Translation

要了解免疫反应和行为之间的联系，我们描述了一种方法来测量运动的行为中<em>果蝇</em以及细菌感染的免疫反应能力的苍蝇安装监控求生存，细菌负荷，并实时活动的一个关键的调节先天免疫，NFκB。

Tags

Quantitative MeasurementImmune ResponseSleepDrosophilaInfectionExcess SleepMammalsDrosophila MelanogasterRobust Immune SystemMultidisciplinary ApproachLocomotor BehaviorPathogenic Strain Of BacteriaDuration Of SurvivalImmune FunctionNFκBTranscription FactorInnate Immune ResponseBacterial ClearanceResistance To InfectionTolerance To Infection

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