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T Lenfositler doğru İsteyerek Pluripotent Kök Hücrelerinin Yönetmen Farklılaşma
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Chapters
- 00:05Title
- 01:10Cell Culture and In vitro Programming
- 02:15In vivo Maturation of Partially Differentiated iPS Cells
- 03:36In vivo Programming
- 04:51Adoptive Transfer and Peptide Stimulation
- 05:50In vivo Killing Assay
- 06:47Intraperitoneal Tumor Cell Count and Infiltrating Tumor Cell Identification
- 08:43Results: In vivo Differentiation of TCR Gene-transduced iPS Cells into Functional Ag-specific CTLs
- 12:25Conclusion
Indüklenmiş pluripotent kök (iPS) hücrelerden T lenfositlerin Nesil T hücre tabanlı immünoterapi için embriyonik kök hücreler kullanarak alternatif bir yaklaşım verir. Yöntem kullanılarak ya da göstermektedir<em> In vitro</em> Veya<em> In vivo</em> Indüksiyon sistemi, iPS hücreleri konvansiyonel ve antijen spesifik hem T lenfositlerin içine ayırt edebiliyoruz.
Tags
Directed DifferentiationInduced Pluripotent Stem CellsT LymphocytesAdoptive Cell TransferAntigen-specific CD8+ Cytotoxic T LymphocytesT Cell ReceptorsCytotoxinsCytokinesHighly Reactive CTLsImmunotherapyHomeostatic CytokinesACT-based TherapiesTCR TransductionSelf-renewable Stem CellsImmune ReconstitutionEmbryonic Stem CellsHematopoietic Stem CellsIn Vitro Cell CultureIPS Cell TechnologyGene Delivery
