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臨床試験および筋萎縮性側索硬化症(ALS)のマウスモデルにおける脊髄の除去
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Clinical Testing and Spinal Cord Removal in a Mouse Model for Amyotrophic Lateral Sclerosis (ALS)
Please note that all translations are automatically generated.
Click here for the English version.
臨床試験および筋萎縮性側索硬化症(ALS)のマウスモデルにおける脊髄の除去
DOI:
10.3791/3936-v
•
12:35 min
•
March 17, 2012
•
René Günther
,
Martin Suhr
,
Jan C. Koch
,
Mathias Bähr
2
,
Paul Lingor
2
,
Lars Tönges
1
Dept. of Neurology
,
University Medicine Göttingen
,
2
DFG Research Center for the Molecular Physiology of the Brain (CMPB)
,
Göttingen, Germany
Chapters
00:02
Title
01:07
Clinical Testing of the SOD G93A Mouse Model of ALS
02:03
Hanging Wire Test
03:05
Rotarod Test
04:30
Spinal Cord Preparation
10:55
Spinal Cord Immunohistochemistry
11:41
Conclusions
Summary
Automatic Translation
English (Original)
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Automatic Translation
筋萎縮性側索硬化症(ALS)のマウスモデルは、臨床的および行動的に検討されている。付随する免疫組織学的分析のための前提条件として、脊髄の調製は、詳細に描かれています。
Tags
Clinical Testing
Spinal Cord Removal
Mouse Model
Amyotrophic Lateral Sclerosis
ALS
Neurodegenerative Disorder
Motoneurons
Familial Mutations
SOD Gene
SOD1 (G93A) Mutation
Overall Survival
Clinical Course
Motor Function
Behavioural Motor Tests
Quantitative Scoring Systems
Immunohistochemical Examination
Spinal Cord Preparation
Dorsal Laminectomy Method
Histological Findings
Therapeutic Options
Human Clinical Trials
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