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Neuroscience
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在小鼠模型中静脉自我管理的方法
JoVE Journal
Neuroscience
Author Produced
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JoVE Journal
Neuroscience
Methods for Intravenous Self Administration in a Mouse Model
Please note that all translations are automatically generated.
Click here for the English version.
在小鼠模型中静脉自我管理的方法
DOI:
10.3791/3739-v
•
12:09 min
•
December 08, 2012
•
Elizabeth K. Kmiotek
,
Corey Baimel
,
Kathryn J. Gill
1
Addictions Unit
,
McGill University Health Centre
Chapters
00:00
Title
00:51
Preparation of Catheter Accessories
02:17
Catheter Preparation
02:43
Anesthesia
03:19
Surgery
11:15
Recovery
11:27
Conclusion
Summary
Automatic Translation
English (Original)
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Automatic Translation
的静脉-的管理(IVSA)的范式被认为是研究在啮齿类动物中滥用药物的补强性的黄金标准。这手稿列出了实验步骤和手术技术必要获得可靠的IVSA的数据。特别突出,细致的导管植入术和维护。
Tags
Intravenous Self-administration
IVSA Paradigm
Drug Reinforcement
Drugs Of Abuse
Cocaine
Schedule Of Reinforcement
Measurement Of Drug Consumption
Timing And Pattern Of IV Injections
Intravenous Route Of Administration
Confounds Related To First Pass Metabolism Or Taste
Blood And Brain Drug Levels
Catheter Placement During Surgery
Daily Catheter Flushing And Maintenance
Animal Housing And Acclimation Methods
Operant Training
Catheter Implantation Surgery
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