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慢性缩窄大鼠坐骨神经疼痛过敏测试
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JoVE Journal Medicine
Chronic Constriction of the Sciatic Nerve and Pain Hypersensitivity Testing in Rats
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慢性缩窄大鼠坐骨神经疼痛过敏测试

DOI:
10.3791/3393-v

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08:23 min

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March 13, 2012

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, ,
1School of Medical Sciences,University of New South Wales

Chapters

  • 00:05Title
  • 01:43Sciatic Nerve Chronic Constriction
  • 04:53Measurements of Mechanical Withdrawal Threshold and Thermal Withdrawal Latency
  • 06:54Representative Results
  • 07:35Conclusion

Summary

Automatic Translation

Automatic Translation

由于手术简单和健壮的行为结果，坐骨神经慢性缩窄是神经​​痛卓越的动物模型之一。手术后24小时内，疼痛过敏建立并可以使用冯弗雷触觉（机械测试）和足底的镇痛米（热试验）的定量测​​定。

Tags

Chronic ConstrictionSciatic NervePain HypersensitivityNeuropathic PainCentral Nervous SystemPeripheral Nervous SystemSymptomsAllodyniaHyperalgesiaAnimal ModelsChronic Constriction InjuryCCIAnaesthesiaSkin IncisionChromic Gut LigaturesEpineural Blood FlowSuturesStaplesRecovery From SurgeryPain Hypersensitivity TestingBehavioural Testing

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