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Journal
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Neuroscience
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肖尔自动数字化的神经元形态分析,多尺度
JoVE Journal
Neuroscience
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JoVE Journal
Neuroscience
Automated Sholl Analysis of Digitized Neuronal Morphology at Multiple Scales
Please note that all translations are automatically generated.
Click here for the English version.
肖尔自动数字化的神经元形态分析,多尺度
DOI:
10.3791/2354-v
•
11:41 min
•
November 14, 2010
•
Melinda K. Kutzing*
1,2
,
Christopher G. Langhammer*
1,2
,
Vincent Luo
,
Hersh Lakdawala
,
Bonnie L. Firestein
1
Department of Cell Biology and Neuroscience
,
Rutgers University
,
2
Graduate Program in Biomedical Engineering
,
Rutgers University
Chapters
00:00
Title
00:20
Introduction
01:20
Preparations for Automated Sholl Analysis
02:14
Tracing Neurons in NeuronJ
04:52
Using Bonfire to Build Preliminary .swc Files from NeuronJ Data
06:27
Using NeuronStudio to Finalize .swc Files
07:57
Using ‘bonfire’ to Extract Morphological Data and ‘bonfire_results’ to View the Data
09:06
Using ‘bonfire_export’ to Export Data into Excel
11:21
Conclusion
Summary
Automatic Translation
English (Original)
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Automatic Translation
我们已经开发出一种计算机程序来分析神经元的形态。在两个现有的开源分析工具的结合,我们的计划执行肖尔,分析和确定的突起,分支点和突起的提示。进行分析,使地方在突起的形态变化可以观察。
Tags
Automated Sholl Analysis
Digitized Neuronal Morphology
Multiple Scales
Neurons
Function
Communication
Inputs
Action Potentials
Neurites
Information Processing
Dendrite Morphologies
Signaling
Specialized Functions
Neuronal Network
Alterations In Morphology
Fragmentation
Branching Patterns
Disease States
Alzheimer’s Disease
Schizophrenia
Mental Retardation
Factors Shaping Dendrite Morphologies
Nervous System Function And Dysfunction
Sholl Analysis
Counting Neurites And Branch Tips
Axons
Time-consuming Analysis
Variability
Experimenter Bias
Inconsistency
Bonfire Program
Article
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