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体内近红外荧光（NIRF）血管内分子成像炎性斑块，多式联运方针成像动脉粥样硬化
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JoVE Journal Medicine
In vivo Near Infrared Fluorescence (NIRF) Intravascular Molecular Imaging of Inflammatory Plaque, a Multimodal Approach to Imaging of Atherosclerosis
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体内近红外荧光（NIRF）血管内分子成像炎性斑块，多式联运方针成像动脉粥样硬化

DOI:
10.3791/2257-v

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09:43 min

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August 04, 2011

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, , , , , ,
1Cardiovascular Research Center and Cardiology Division, Massachusetts General Hospital,Harvard Medical School, 2Institute for Biological and Medical Imaging,Helmholtz Zentrum München und Technische Universität München, 3Department of Electrical and Computer Engineering,Northeastern University

Chapters

  • 00:05Title
  • 02:04Integrated Multi-modal Imaging of Rabbit Atheromata
  • 04:43Ex Vivo Fluorescence Reflectance Imaging (FRI) of Dissected Aorta and Iliac Arteries
  • 06:20Analyses and Integration of Multi-modal Images (Angiography, IVUS, NIRF, and FRI)
  • 07:37Representative Results
  • 08:35Conclusion

Summary

Automatic Translation

Automatic Translation

我们详细介绍了一个新的近红外荧光（NIRF）导管二维血管内斑块的生物学分子成像<em>在体内</em>。 NIRF导管可以想像报告斑块狂热的激活和有针对性的近红外荧光存在的关键生物过程，如炎症。导管采用临床工程和电力的需求和目标是应用在人体冠状动脉。以下的研究描述了一个利用了一种新型的多模态成像战略<em>在体内</em>血管NIRF导管的形象和量化水解积极发炎兔atheromata炎性斑块。

Tags

In VivoNear Infrared FluorescenceNIRFIntravascular Molecular ImagingInflammatory PlaqueAtherosclerosisVascular ResponseInjuryInflammatory ResponseMacrophagesAccumulationLipid-laden Intra-luminal PlaqueSmooth Muscle Cell ProliferationNarrowing Of Vessel LumenVulnerable PlaquesAcute Myocardial InfarctionMolecular ImagingClinical ToolResearch ToolVisualization Of InflammationBiological ProcessesHigh-risk PlaquesPharmacotherapeuticsMRIPETCarotid ArteriesCoronary ArteriesHigh-resolution Optical Imaging Strategies

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