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在小鼠体内的横向主动脉缩窄
JoVE Journal
Biology
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JoVE Journal
Biology
Transverse Aortic Constriction in Mice
Please note that all translations are automatically generated.
Click here for the English version.
在小鼠体内的横向主动脉缩窄
DOI:
10.3791/1729-v
•
08:25 min
•
April 21, 2010
•
Angela C. deAlmeida
,
Ralph J. van Oort
,
Xander H.T. Wehrens
2
1
Department of Molecular Physiology and Biophysics
,
Baylor College of Medicine (BCM)
,
2
The Margaret M. and Albert B. Alkek Department of Medicine
,
Baylor College of Medicine (BCM)
Chapters
00:00
Title
00:42
Introduction
01:10
Preparing the Operating Field
02:02
Preparing and Intubation of Mice
03:25
Ligation of the Transverse Aorta
06:31
Confirmation of Successful Ligation of the Transverse Aorta
07:32
Results of a Successful Transverse Aortic Constriction
08:02
Conclusion
Summary
Automatic Translation
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Automatic Translation
横向主动脉缩窄(TAC)的鼠标是一种常用的实验模型研究的内在机制,心肌肥厚和心力衰竭的发展。在这里,我们描述程序,创建一个小鼠心肌肥厚的重复性程度的主动脉。
Tags
Transverse Aortic Constriction
TAC
Pressure Overload
Cardiac Hypertrophy
Heart Failure
Murine TAC Model
Cardiovascular Diseases
Signaling Processes
Left Anterior Descending Coronary Artery Occlusion
Reproducible Model
Gradual Time Course
Surgical Procedure
High Frequency Doppler Probe
Blood Flow Velocities
Left Ventricular Hypertrophy
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