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创建小鼠实验与弹性蛋白酶的腹主动脉瘤
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Biology
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JoVE Journal
Biology
Creation of Murine Experimental Abdominal Aortic Aneurysms with Elastase
Please note that all translations are automatically generated.
Click here for the English version.
创建小鼠实验与弹性蛋白酶的腹主动脉瘤
DOI:
10.3791/1280-v
•
10:23 min
•
July 23, 2009
•
Junya Azuma
,
Tomoko Asagami
,
Ronald Dalman
,
Philip S. Tsao
1
Department of Cardiovascular Medicine
,
Stanford University School of Medicine
,
2
Department of Vascular Surgery
,
Stanford University School of Medicine
Chapters
00:05
Title
00:57
Introduction
01:31
Preparing the Mouse for Surgery
03:16
Surgical Prodcedure
09:20
Representative Results
09:50
Conclusion
Summary
Automatic Translation
English (Original)
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Automatic Translation
该视频演示了如何通过瞬态下腹段腹主动脉腔内灌注到猪胰弹性蛋白酶诱导小鼠腹主动脉瘤(AAA)的。该模型已添加到AAA的病理学由于出现了大量的转基因和基因敲除小鼠的广泛的洞察力的能力。
Tags
Murine
Experimental
Abdominal Aortic Aneurysms
Elastase
Intraluminal Infusion
Porcine Pancreatic Elastase
Infrarenal Segment
Abdominal Aorta
Animal Model
Disrupted Nature Of Elastin
Pathobiology Of AAA
Transgenic Mice
Gene Knockout Mice
Therapeutic Agents
Elastase Infusion AAA Procedure
Laparotomy
Sterile Conditions
Operating Stereomicroscope
Ligatures
Aortotomy
Polyethylene Tubing
Perfusion Catheter
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