Mechanism of Kemeng Fang's Inhibition of Podocyte Apoptosis in Rats with Membranous Nephropathy through the PI3K/AKT Signaling Pathway

Fan Li; Chengji Cui; Haiyan Yu; Chunguang Yi; Guang Ta; Jie Wang; Xu Huang; Yutong Liu; Shoulin Zhang

doi:10.3791/67170

Traditional Medicine and PI3K/AKT Pathway Activation in Membranous Nephropathy

August 23, 2024

Author Spotlight: Advancing Treatments for Membranous Nephropathy with Chinese Traditional Medicine

00:00 min

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Fan Li, Chengji Cui, Haiyan Yu, Chunguang Yi, Guang Ta, Jie Wang, Xu Huang, Yutong Liu, Shoulin Zhang

¹College of Integrated Chinese and Western Medicine,Changchun University of Chinese Medicine, ²Nephropathy Department,the Affiliated Hospital to Changchun University of Chinese Medicine, ³College of Traditional Chinese Medicine,Changchun University of Chinese Medicine, ⁴Internal Medicine Intensive Care Unit,the Affiliated Hospital to Changchun University of Chinese Medicine

Summary

The present protocol describes the establishment of a membranous nephropathy (MN) animal model, and how Kemeng Fang’s inhibition reduces MN rat podocyte apoptosis by activating the PI3K/AKT signaling pathway.

Traditional Medicine and PI3K/AKT Pathway Activation in Membranous Nephropathy

Author Spotlight: Advancing Treatments for Membranous Nephropathy with Chinese Traditional Medicine

Summary

Article